Stage W0: living research prototype12 of 30 manuscripts drafted, 0 reviewed; 50 lexicon entries in draftWhat each later stage would need to show

NucLex: Nuclear Medicine Lexicon and Theranostics Ontology

What does it take for two people to mean the same thing?

NucLex is a publication about ontology: the long human effort to name things, relate them, and agree on what a word points at. It is also a proposal to build that shared language, anchored in SNOMED CT, for nuclear medicine, theranostics, and computational nuclear oncology. Begin with an essay, follow an unfamiliar term into a monograph, and check a concept in the lexicon without losing the question you started with.

Lead essayEssayDraft18 min read

Why medicine needs a shared language

A name begins a conversation. A shared concept lets us ask whether we mean the same thing.

Two physicians look at the same scan and disagree about whether a patient has "progressed." They are not disagreeing about the image. They are using one word for two different concepts. This essay follows that ordinary failure back through the story of Babel, the first Greek questions about names and being, and Aristotle's categories, and then separates two questions that medicine keeps confusing: what kinds of things there are, and how we know what we claim.

Reading paths

Drafts are unreviewed; briefs are assignments not yet written

Reference monographs

All twenty
  • MonographDraft15 min read

    Ontology

    Before we can agree about a thing, we have to agree that it is a thing, and what kind of thing it is.

  • MonographDraft15 min read

    Epistemology

    A reading of a scan is a claim to know something. What entitles the reader to make it?

  • MonographDraft15 min read

    Knowledge graphs

    A graph is a way of writing down who is connected to what. It is not a way of knowing whether the connection is real.

  • MonographDraft15 min read

    SNOMED CT and the NucLex niche

    A clinical terminology of several hundred thousand concepts already exists. The question is what a nuclear medicine lexicon should reuse, what it should add, and how it should keep the two apart.

  • MonographDraft14 min read

    FHIR terminology resources

    CodeSystem, ValueSet, and ConceptMap are the three containers that carry meaning between systems. They are not the meaning itself.

  • MonographDraft16 min read

    Precision nuclear oncology

    An individualized question is answered from thousands of records, in several formats, made at different times, by people who did not know the question would be asked.

Commissioned, not yet written

All essays